Posts about macrophage activation
How Itaconate Modifications Control Inflammation and Could Transform Disease Treatment
If you told a biologist 15 years ago that a byproduct of the citric acid cycle could shut down inflammation, they’d probably raise[…]
iNOS suppresses itaconate by directly binding IRG1 in mitochondria, no nitric oxide required
There’s a protein in your immune cells that most biochemistry textbooks treat as well-understood. It’s called inducible nitric oxide synthase, or iNOS, and[…]