Posts about oncometabolite

Dimethyl Itaconate in Cancer Therapy: How It Works and Why It Matters

For decades, itaconate has been known as an immune molecule, something macrophages churn out when they encounter pathogens or inflammation signals. Researchers studied[…]

Itaconate: A Metabolite Driving One of the Deadliest Brain Tumors

Brain tumors are tough to treat. ZFTA-RELA fusion-positive ependymomas are among the worst—affecting mostly children and young adults with few options beyond surgery[…]