Introduction:
HFE-458 (1,1,2,2-Tetrafluoroethyl-2,2,3,3-tetrafluoropropyl ether), a hydrofluoroether (HFE) solvent offered by Symb ChemTech, is gaining prominence as an environmentally responsible alternative for various industrial applications. Its unique properties make it suitable for electronics cleaning and as an additive in lithium-ion battery electrolytes. This article provides a comprehensive overview of HFE-458’s properties, applications, handling, and safety information.
Key Properties:

HFE-458 is a colorless and clear liquid with a characteristic ether-like odor. Its key properties include:
- High Purity: Symb ChemTech’s HFE-458 has a minimum purity of 99.5%.
- Low Impurity Levels: Stringent quality control ensures very low water content (≤ 0.005%) and acidity (≤ 0.0001%).
- Specific Physical Properties:
- Molecular Formula: C₆H₄F₈O
- Molecular Weight: 232.07 g/mol
- CAS No.: 16627-68-2
- Melting Point: -94.27°C
- Boiling Point: 93.17°C
- Density (25°C): 1.533 g/mL
Technical Specifications:
| Item | Specification |
|---|---|
| Appearance | Colorless and clear liquid with the odor of ethers |
| Purity (w/%) | ≥ 99.5 |
| Water Content (w/%) | ≤ 0.005 |
| Acidity (w/%) | ≤ 0.0001 |
Applications:
HFE-458 finds applications in two primary areas:
- Electronics Cleaning: Effective as a cleaning agent for electronic products, particularly for circuit boards, removing flux residues, oils, and other contaminants. Its favorable environmental profile makes it a suitable replacement for ozone-depleting substances.
- Lithium-Ion Battery Electrolyte Additive: Can be used as an additive in lithium-ion battery electrolytes to improve the electrolyte’s cut-off voltage, potentially enhancing battery performance and safety.
Handling and Safety Precautions:
- Anesthetic Effects: HFE-458 has anesthetic properties. Therefore, adequate ventilation is crucial during use.
- Personal Protective Equipment (PPE): Operators should wear appropriate PPE, including rubber gloves, chemical safety glasses, filtered gas masks, and anti-virus protective overalls.
- Safety Data Sheet (SDS): It is essential to carefully read and understand the SDS before using HFE-458. The SDS contains detailed information on hazards, handling procedures, first aid measures, and emergency response protocols.
Packaging, Storage, and Transportation:
- Packaging: HFE-458 is packaged in stainless steel pressurized drums, available in 250 kg/drum and 25 kg/drum sizes.
- Storage: Store in a cool, well-ventilated area. Keep drums tightly closed and avoid mixing with oxidants. Prevent contact with heat sources and flames.
- Transportation: Transport HFE-458 in logistics vehicles specifically designated for hazardous chemicals, adhering to all relevant transportation regulations.
Symb ChemTech‘s HFE-458 is a versatile hydrofluoroether solvent with important applications in electronics cleaning and lithium-ion battery technology. Due to its anesthetic properties, proper handling and storage are crucial. Always consult the SDS for complete safety information.

