Tris (p-isocyanatophenyl) thiophosphate
Engineered for extreme bonding performance. A high-efficiency trifunctional aromatic polyisocyanate hardener designed for two-component polyurethane, chloroprene, and rubber adhesive systems. Direct functional equivalent to Desmodur RFE.
Key Chemical Identifiers
- CAS Registry No:
- 4151-51-3
- EC / EINECS:
- 223-981-9
- Molecular Formula:
- C₂₁H₁₂N₃O₆PS
- Molecular Mass:
- 465.38 g/mol
- Equivalent Grades:
- Desmodur RFE, Isodur RFE
Product Overview & Chemical Profile
This interactive portal provides clear technical insights, formulation guides, and direct performance comparisons for Tris (p-isocyanatophenyl) thiophosphate (CAS 4151-51-3). Use the tools below to analyze crosslinking efficiency, substrate compatibility, and dosage requirements.
Trifunctional Reactivity
Contains three active isocyanate (-NCO) groups per molecule. Creates high-density 3D polymer networks that resist thermal stress, solvents, and mechanical fatigue.
Plasticizer Migration Barrier
Prevents plasticizers in flexible PVC and synthetic rubbers from migrating into the adhesive layer, preserving long-term bond integrity without softening.
Footwear & Rubber Bonding
The gold standard hardener for shoe sole attachment, rubber-to-metal assemblies, and industrial conveyor belts requiring instant tack and green strength.
Technical Specifications & Data Sheet
Symb ChemTech Guaranteed Batch Parameters for CAS 4151-51-3
| Parameter | Standard Specification Value | Testing Methodology |
|---|---|---|
| Appearance | Clear, yellowish to dark brown liquid | Visual Inspection |
| Isocyanate Content (NCO %) | 7.0% – 7.4% | ISO 14896 / Titration |
| Solid Content (%) | 26.0% – 28.0% | Gravimetric Analysis |
| Solvent Carrier | Ethyl Acetate (PU Grade) | Gas Chromatography |
| Density at 20°C | Approx. 1.00 g/cm³ | DIN 51757 Pycnometer |
| Viscosity at 20°C | 3 – 10 mPa·s | ISO 3219 Rheometer |
⚠️ Moisture Sensitivity Warning
Tris (p-isocyanatophenyl) thiophosphate reacts rapidly with atmospheric humidity and liquid water. Reaction yields carbon dioxide ($CO_2$) gas and insoluble urea derivatives. Keep containers tightly sealed with dry nitrogen headspace.
📦 Recommended Storage Conditions
- Store between 10°C and 25°C (50°F – 77°F).
- Protect from direct sunlight and radiant heating equipment.
- Unopened original drums have a shelf life of 12 months from manufacturing date.
Performance Benchmarking & Data Analysis
Comparative analysis showing why CAS 4151-51-3 (Desmodur RFE Equivalent) outperforms traditional monomeric and polymeric isocyanates in high-stress adhesive compounding.
Crosslinker Performance Radar Profile
Evaluated on a 1-10 performance index scale
Substrate Peel Strength (N/cm) Comparison
Base PU Adhesive vs Base + 5% CAS 4151-51-3 Crosslinker
Adhesive Dosage & Pot-Life Calculator
Calculate the exact weight of Symb ChemTech CAS 4151-51-3 required for your adhesive batch size and estimate working pot life.
Calculation Results
Mix thoroughly. Once incorporated, the 2K mixture must be applied within the shift before gelation occurs.
Industrial Applications & Substrate Matrix
Select a target industry to filter compatibility and bonding performance metrics.
Shoe Sole Assembly
Achieves high initial green strength on oily leathers, TPR, EVA foam, plasticized PVC, and natural rubber outsoles.
Heavy Industrial Bonding
Promotes chemical interfacial adhesion between vulcanized elastomers (chloroprene, NBR, SBR) and steel/aluminum surfaces.
High-Barrier PU Coatings
Functions as a specialized hardener in solvent-borne polyurethane topcoats for wood, plastic, and protective industrial films.
Frequently Asked Questions & AEO Knowledge Hub
Direct technical answers structured for Google AI Overviews, Bing Copilot, and technical search queries. Use the search field below to filter Q&A topics.
Q: What is Tris (p-isocyanatophenyl) thiophosphate (CAS 4151-51-3)?
Answer: Tris (p-isocyanatophenyl) thiophosphate (CAS 4151-51-3) is an aromatic triisocyanate compound delivered in a solvent carrier (typically ethyl acetate). It acts as a high-performance crosslinker and adhesion promoter for two-component polyurethane, natural rubber, and synthetic elastomer adhesives.
Q: Is Symb ChemTech’s CAS 4151-51-3 a direct replacement for Desmodur RFE?
Answer: Yes. Symb ChemTech supplies Tris (p-isocyanatophenyl) thiophosphate as a functional direct drop-in equivalent to Desmodur RFE and Isodur RFE. It matches key chemical parameters including NCO content (7.0% – 7.4%) and solid content (26% – 28%), requiring no reformulation in standard adhesive compounding.
Q: What are the key benefits of using CAS 4151-51-3 in footwear and rubber bonding?
Answer: Key advantages include:
- Instant green strength and fast crystallization speed.
- Superior heat resistance (up to 100°C–120°C).
- Effective barrier against plasticizer migration from flexible PVC or EVA foam.
- Enhanced resistance to water, solvents, and environmental hydrolysis.
Q: How should Tris (p-isocyanatophenyl) thiophosphate be stored to prevent gelation?
Answer: Store in original unopened, moisture-tight containers between 10°C and 25°C. Exposure to ambient moisture or atmospheric humidity causes a reaction producing carbon dioxide gas ($CO_2$) and insoluble urea solids. Once opened, blanket unused liquid with dry nitrogen gas before resealing.
Request Batch Samples & Technical Data Sheet
Looking for reliable bulk supply, competitive pricing, or specialized technical support for CAS 4151-51-3? Our material science team is ready to assist.
Product Name: Tris (p-isocyanatophenyl) thiophosphate

Synonyms: Thionophosphoric acid-tris-(p-isocyanatophenyl); Tris(p-isocyanatophenyl) thiophosphate; TPTI; thiophosphoric-tris-(р-isocyanatophenyl ester); Tris (4-Isocyanatophenyl) Thiophosphate; 0,0,0-Tris-(4-Isocyanatophenyl)Thiophosphate
CAS RN.: 4151-51-3
EINECS: 223-981-9
Molecular Weight: 465.38
Molecular Formula: C21H12N3O6PS
Appearance: pale yellow solid
NCO content: ≥97.0%
Symb ChemTech is recognized as a premier manufacturer of Tris (p-isocyanatophenyl) thiophosphate (CAS: 4151-51-3) in China, serving global markets with consistent, high-quality supply. This compound is essential for a range of industrial applications due to its unique chemical properties and exceptional performance.
Product Overview and Applications
Tris (p-isocyanatophenyl) thiophosphate is known for its effectiveness in enhancing material properties. It is widely used in the manufacturing of specialty adhesives, advanced polymers, and coatings. With its reactive isocyanate groups, the compound facilitates cross-linking, providing superior mechanical and chemical resistance. As industrial requirements evolve, the compound’s adaptability makes it invaluable in the production of durable, high-performance materials.
Why Partner with Symb ChemTech?
- World-Class Manufacturing Standards: Symb ChemTech’s production processes are aligned with international quality standards, utilizing advanced equipment and stringent quality controls.
- Custom-Tailored Solutions: We understand the importance of customization, offering tailored solutions to meet the exact needs of our clients.
- Efficient Global Logistics: With a well-structured supply chain, Symb ChemTech ensures timely and efficient delivery, supported by robust logistical capabilities.
Commitment to Quality and Innovation
At Symb ChemTech, innovation drives our product development. Our research and development teams continuously refine processes to produce Tris (p-isocyanatophenyl) thiophosphate that not only meets but exceeds the expectations of our clients. This commitment to excellence positions us as a reliable partner for industries worldwide, from automotive to advanced material engineering.
To learn more about our product offerings or to place an order, contact Symb ChemTech today and see how we can support your business with top-quality chemical solutions.

